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| Product Name | Recombinant Human Hypoxia-inducible factor 1-alpha protein |
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| Description | 579-826aa; Partial. MW: 31.1kD. Purity >90% as determined by SDS-PAGE. Functions as a master transcriptional regulator of the adaptive response to hypoxia. Under hypoxic conditions, activates the transcription of over 40 genes, including erythropoietin, glucose transporters, glycolytic enzymes, vascular endothelial growth factor, HILPDA, and other genes whose protein products increase oxygen delivery or facilitate metabolic adaptation to hypoxia. Plays an essential role in embryonic vascularizat |
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| Size | 0.01 mg, 0.05 mg, 0.1 mg, 0.2 mg, 0.5 mg |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | [ARNT-interacting protein; Basic-helix-loop-helix-PAS protein MOP1; Class E basic helix-loop-helix protein 78; bHLHe78; Member of PAS protein 1; PAS domain-containing protein 8] |
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| Gene, Accession, CAS # | HIF1A, Gene ID: 3091, Accession: NP_001230013.1 |
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| Catalog # | MBS960172 |
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| Order / More Info | Recombinant Human Hypoxia-inducible factor 1-alpha protein from MYBIOSOURCE INC. |
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| Product Specific References | Hypoxia-inducible factor 1 is a basic-helix-loop-helix-PAS heterodimer regulated by cellular O2 tension.Wang G.L., Jiang B.-H., Rue E.A., Semenza G.L.Proc. Natl. Acad. Sci. U.S.A. 92:5510-5514(1995) |
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