| 产品详情 |
| Edit |   |
|---|
| Product Name | Imperatorin |
|---|
| Description | A furanocoumarin with diverse biological activities; decreases MCL-1 protein levels and increases mitochondrial membrane depolarization and apoptosis in R-HepG2 cells, an effect that can be reversed by overexpression of MCL-1; inhibits the growth of doxorubicin-resistant and -sensitive HepG2 cells (IC50s = 28.1 and 43.3 µM, respectively); reduces tumor growth in an R-HepG2 mouse xenograft model at 50 mg/kg; inhibits LPS-induced increases in p38 MAPK, JNK, and IκBα phosphorylation, TNF-α, IL-6, and IL-1β protein levels, and nuclear localization of NF-κB p65 in RAW 264.7 macrophages; scavenges DPPH and ABTS radicals (EC50s = 19.48 and 10.93 µM, respectively); has antibacterial, antiviral, and anticonvulsant activities |
|---|
| Size | 10 mg |
|---|
| Concentration | n/a |
|---|
| Applications | n/a |
|---|
| Other Names | Marmelosin|NSC 402949 |
|---|
| Gene, Accession, CAS # | CAS: 482-44-0 |
|---|
| Catalog # | 26070-10 |
|---|
| Price | |
|---|
| Order / More Info | Imperatorin from CAYMAN CHEMICAL COMPANY |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|