产品名称 ALOX5 (pS523) Antibody from ABBEXA
产品货号 abx012014
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 ABBEXA
产品概述
产品详情
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Antigenic SpecificityALOX5 (pS523)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat
Isotypen/a
Formataffinity purified
Size100 µg
Concentrationn/a
ApplicationsWB. RUO
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionPhospho-ALOX5 (Ser523) Antibody detects endogenous levels of ALOX5 only when phosphorylated at Sersine 523. This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5 (S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5 (S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined.
Immunogenn/a
Other Names5-LO; 5-LOX; 5LPG; LOG5; MGC163204; ALOX5; Arachidonate 5-lipoxygenase; 5-lipoxygenase
Gene, Accession #ALOX5, Gene ID: 240, SwissProt: P09917
Catalog #abx012014
Price
Order / More InfoALOX5 (pS523) Antibody from ABBEXA
Product Specific Referencesn/a
产品资料