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| Antigenic Specificity | Desmoglein 2 (DSG2) (aa 1104-1118), (C-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Desmoglein-2 is a protein that in humans is encoded by the DSG2 gene. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in DSG2 display a high degree of penetrance. Disease expression was of variable severity with LV involvement a prominent feature. The low prevalence of classical ECG changes highlights the need to expand current diagnostic criteria to take account of LV disease, childhood disease expression, and incomplete penetrance. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human Desmoglein 2(1104-1118aa STRVTKHSTVQHSYS), different from the related mouse and rat sequences by one amino acid. |
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| Other Names | DSG2|dsc|dsga|si:dkeyp-51f12.6|wu:fj23f02|ARVC10|ARVD10|CDHF5|CMD1BB|HDGC|AA408168|D18Ertd293e |
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| Gene, Accession # | Gene ID: 1829,307562 |
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| Catalog # | ABIN1706159 |
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| Price | |
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| Order / More Info | Desmoglein 2 (DSG2) (aa 1104-1118), (C-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 1612610 |
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