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| Product Name | CD279-muIg-purified Preservative Free |
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| Description | Purified Preservative Free. Information: Human CD279 (PD-1, Programmed death 1) is a 55 kd Ig superfamily member with similarity to CD28 and CD152(CTLA-4). It is expressed on activated T and B and myeloid cells, and engagement by its ligands PD-L1 (CD274, B7-H1) or PD-L2 (B7-DC) can inhibit proliferation and cytokine expression. In mice blockade of PD-1 ligand interaction has been used to augment T cell anti cancer responses (1,2,3). Recombinant CD279-muIg binds to recombinant CD274 and C |
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| Size | 0.025 mg |
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| Concentration | 0.5 mg/ml |
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| Applications | ELISA (EIA), Flow Cytometry (FC/FACS) |
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| Other Names | [Human CD279(PD-1)-muIg Fusion Protein] |
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| Gene, Accession, CAS # | [CD279] |
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| Catalog # | MBS666786 |
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| Order / More Info | CD279-muIg-purified Preservative Free from MYBIOSOURCE INC. |
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| Product Specific References | 1) MA Curran, Allison JP, et al. (2010) PNAS 107(9): 4275-80. 2) Mangsbo SM, TH Totterman, et al. (2010) J Immunotherapy 33(3):225. 3) Hirano F, L Chen, et al. (2005) Canc Res 65: 1089. |
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