| Edit |   |
|---|
| Antigenic Specificity | CASPASE-8 |
|---|
| Clone | polyclonal |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | mouse, rat |
|---|
| Isotype | n/a |
|---|
| Format | n/a |
|---|
| Size | 0.1 mg |
|---|
| Concentration | IgG concentration 1.0 mg/ml |
|---|
| Applications | Western Blot (WB) |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | RABBIT ANTI CASPASE-8 (C-TERMINAL). This item recognises an epitope within the c-terminal region (CT) of caspase-8, otherwise known as Fas-linked ICE-like protease (FLICE), which shares homology with both Fas-associated via death domain (FADD) and the ICE/Ced-3 family of cysteine proteases.Caspase-8 is classified as an initiator caspase and acts as the most upstream trigger of Fas-Receptor (CD95) and tumour necrosis factor receptor 1 (TNFR1) mediated apoptosis. Upon activation, the cell death re |
|---|
| Immunogen | A 16 amino acid peptide located near the carboxy-terminus of human caspase-8 isoform A. |
|---|
| Other Names | caspase-8 isoform C; Caspase-8; caspase-8; FADD-homologous ICE/CED-3-like protease; FADD-like ICE; ICE-like apoptotic protease 5; MACH-alpha-1/2/3 protein; MACH-beta-1/2/3/4 protein; MORT1-associated ced-3 homolog; apoptotic cysteine protease; apoptotic protease Mch-5; caspase 8, apoptosis-related cysteine protease; caspase 8, apoptosis-related cysteine peptidase; Apoptotic cysteine protease; Apoptotic protease Mch-5; CAP4; FADD-homologous ICE/ced-3-like protease; FADD-like ICE; FLICE; ICE-like |
|---|
| Gene, Accession # | Gene ID: 841, NCBI: NP_001073593.1, UniProt: Q14790 |
|---|
| Catalog # | MBS224284 |
|---|
| Price | |
|---|
| Order / More Info | CASPASE-8 Antibody from MYBIOSOURCE INC. |
|---|
| Product Specific References | n/a |
|---|