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| Antigenic Specificity | Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 (SLC6A4) (aa 7-24), (N-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | SLC6A4(Solute carrier family 6, member 4), also known as SERT(serotonin transporter), is a monoamine transporter protein. The SLC6A4 gene spans 31 kb and contains 14 exons. This protein integral membrane protein that transports the neurotransmitter serotonin from synaptic spaces into presynaptic neurons. This transport of serotonin by the SERT protein terminates the action of serotonin and recycles it in a sodium-dependent manner. This protein is the target of many antidepressant medications, including those of the SSRI class. It is a member of the sodium:neurotransmitter symporter family. A repeat length polymorphism in the promoter of this gene has been shown to affect the rate of serotonin uptake and may play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, post-traumatic stress disorder and depression-susceptibility in people experiencing emotional trauma. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of rat Serotonin transporter(7-24aa NSQKVLSECKDREDCQEN), different from the related mouse sequence by one amino acid. |
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| Other Names | CG4545|DmSERT|DmSerT|Dmel\\CG4545|SERT|Sert|dSERT|dSERT1|dSerT|dSert|dsert|SLC6A4|HTT|5-HTT|AI323329|Htt|5-HTTLPR|5HTT|OCD1|SERT1|hSERT |
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| Gene, Accession # | Gene ID: 25553 |
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| Catalog # | ABIN1673185 |
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| Price | |
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| Order / More Info | Solute Carrier Family 6 (Neurotransmitter Transporter, serotonin), Member 4 (SLC6A4) (aa 7-24), (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 11920155, 8929413, 10713891 |
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