产品名称 Solute Carrier Family 1 (Neuronal/epithelial High Affinity Glutamate Transporter, System Xag), Member 1 (SLC1A1) (Extracellular Domain) Antibody from ANTIBODIES-ONLINE GmbH
产品货号 ABIN350315
产品价格 现货询价,电话:010-67529703
产品规格 100 µL
产品品牌 ANTIBODIES-ONLINE GmbH
产品概述
产品详情
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Antigenic SpecificitySolute Carrier Family 1 (Neuronal/epithelial High Affinity Glutamate Transporter, System Xag), Member 1 (SLC1A1) (Extracellular Domain)
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat, mouse
Isotypen/a
Formatserum
Size100 µL
Concentrationn/a
ApplicationsImmunohistochemistry (IHC),Western Blotting (WB)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionFunction: Transports L-glutamate and also L- and D-aspartate. Essential for terminating the postsynaptic action of glutamate by rapidly removing released glutamate from the synaptic cleft. Acts as a symport by cotransporting sodium. Negatively regulated by ARL6IP5. Defects in SLC1A1 may be a cause of dicarboxylicamino aciduria, also known as glutamate-aspartate transport defect. This is as defect in renal and probably intestinal transport of glutamic and aspartic acids and is associated with moderate hyperprolinemia.Subcellular location: Membrane, Multi-pass membrane protein.Tissue specificity: Expressed in all tissues tested including liver, muscle, testis, ovary, retinoblastoma cell line, neurons and brain (in which there was dense expression in substantia nigra, red nucleus, hippocampus and in cerebral cortical layers). Also known as: Sodium-dependent glutamate/aspartate transporter 3, Excitatory amino-acid carrier 1, Neuronal and epithelial glutamate transporter, Solute carrier family 1 member 1, EAAC1, EAAT3, SLC1A1.
ImmunogenA synthetic peptide from extracellular domain of human EAAT3 (aa region 150-200) conjugated to an immunogenic carrier protein was used as the antigen. The peptide shares 96% identity with rat and mouse sequence.
Other NamesGB16911|EAAT3|SLC1A2a|zgc:91959|EAAC1|SCZD18|D130048G10Rik|EAAC2|MEAAC1|Eaac1|Eaat3|REAAC1
Gene, Accession #Gene ID: 6505,20510,25550
Catalog #ABIN350315
Price
Order / More InfoSolute Carrier Family 1 (Neuronal/epithelial High Affinity Glutamate Transporter, System Xag), Member 1 (SLC1A1) (Extracellular Domain) Antibody from ANTIBODIES-ONLINE GmbH
Product Specific ReferencesPubMed: 7521911, 15164053, 7914198, 7859077, 11317217
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