产品详情 |
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Antigenic Specificity | Syntaxin |
Clone | SP-6 |
Host Species | Mouse |
Reactive Species | mouse, rat |
Isotype | n/a |
Format | Atto 680 conjugate |
Size | 100 µg |
Concentration | n/a |
Applications | Immunocytochemistry (ICC),Immunofluorescence (IF),Immunohistochemistry (IHC),Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Syntax ins are a family of membrane integrated Q-SNARE proteins participating in exocytosis. They possess a single C-terminal transmembrane domain, a SNARE domain, and an N-terminal regulatory domain. This SNARE domain binds to synaptobrevin and SNAP-25 to form the SNARE complex. Support of syntaxin's involvement in vesicular transport and neurotransmission includes the requirement of its yeast homologs, SSO 1 and 2, in targeting and fusion of Golgi-derived vesicles with the plasma membrane. Syntaxin also provides the target pf clostridial neurotoxin C1, which blocks neurotransmitter release. The formation of 20S complex involves the interaction of VAMP with syntaxin through an ATP-dependent reaction modulated by synaptotagmin, SNAP-25, a-SNAP and NSF.Cellular Localization: Membrane |
Immunogen | Raised against synaptic vesicle-containing fractions of immunoprecipitated human brain homogenate |
Other Names | CG11278|Dm Syx13|DmSyx13|Dmel\\CG11278|SYN13|Syx|ff16|ff16 (69D1-70A2)|l(3)01470|syx13|Tb03.5L5.810 |
Gene, Accession # | n/a |
Catalog # | ABIN2484726 |
Price | |
Order / More Info | Syntaxin Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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