| 产品详情 |
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| Antigenic Specificity | SMAC/DIABLO |
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| Clone | 2D12 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG2b |
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| Format | n/a |
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| Size | 0.1 mg |
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| Concentration | n/a |
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| Applications | ELISA; Western Blot |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mouse Anti-Human SMAC/DIABLO-UNLB. Specificity: Human SMAC/DIABLOSMAC/DIABLO (second mitochondria-derived activator of caspase/direct IAP-binding protein with low PI) is a mitochondrial protein that functions as a regulatory component during apoptosis. It is encoded by a nuclear gene and is subsequently imported into the mitochondria where the N-terminus is removed generating the mature form of the molecule. SMAC/DIABLO has been shown to neutralize the antiapoptotic effect of the inhibitor o |
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| Immunogen | n/a |
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| Other Names | Smac/DIABLO-S protein; Diablo homolog (Drosophila); diablo homolog, mitochondrial; 0610041G12Rik; OTTHUMP00000211306; OTTHUMP00000211307; OTTHUMP00000211309; OTTHUMP00000239748; OTTHUMP00000239749; mitochondrial Smac protein; direct IAP-binding protein with low pI; second mitochondria-derived activator of caspase; diablo, IAP-binding mitochondrial protein, DIABLO; DIABLO; SMAC; SMAC3; DIABLO-S; FLJ10537; FLJ25049 |
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| Gene, Accession # | Gene ID: 56616, UniProt: Q502X2 |
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| Catalog # | MBS670144 |
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| Price | |
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| Order / More Info | SMAC/DIABLO Antibody from MYBIOSOURCE INC. |
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| Product Specific References | 1. Verhagen, A.M., P.G. Ekert, M. Pakusch, J. Silke, L.M. Connolly, G.E. Reid, R.L. Moritz, R.J. Simpson, and D.L. Vaux. 2000. Cell 102:43. 2. Hu, S., and X. Yang. 2003. J. Biol. Chem. 278:10055. 3. Du, C., M. Fang, Y. Li, L. Li, and X. Wang. 2000. Cell 102:33. 4. Adrain, C., E.M. Creagh and S.J. Martin. 2001. EMBO. 20:6627. 5. Srinivasula, S.M., P.Datta, X. Fan, T. Fernandes-Alnemri, Z. Huang, and E.S. Alnemri. 2000. J. Biol. Chem. 275:36152. 6. Ekert, P.G., J. Silke, C.J. Hawkin |
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