产品详情 |
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Antigenic Specificity | BiP |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | mouse, rat, human |
Isotype | n/a |
Format | affinity purified |
Size | 50 µg |
Concentration | n/a |
Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Secretory and transmembrane proteins are synthesized on polysomes and translocated into the endoplasmic reticulum (ER). Inside the ER, these proteins are often modified by disulfide bond formation, amino-linked glycosylation and folding. To help proteins fold properly, the ER contains a pool of molecular chaperones including BiP. BiP was identified as an immunoglobulin heavy chain binding protein in pre-B cells . It was also found to be induced at the protein level by glucose starvation . When protein folding is disturbed inside ER, BiP synthesis is increased. Subsequently, BiP binds to misfolded proteins to prevent them from forming aggregates and assists in proper refolding . Synonyms: HSPA5,BIP,FLJ26106,GRP78,MIF2 , |
Immunogen | Recombinant protein of human BIP |
Other Names | AL022860|AU019543|Bip|D2Wsu141e|D2Wsu17e|Grp78|Hsce70|SEZ-7|Sez7|baffled|mBiP |
Gene, Accession # | Gene ID: 14828 |
Catalog # | ABIN1683665 |
Price | |
Order / More Info | BiP Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | n/a |
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