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| Antigenic Specificity | NF2 (pS518) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 50 µl, 100 µl, 200 µl |
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| Concentration | > 1 mg/ml |
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| Applications | WB, IF/ICC. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | NF2 (pS518) Antibody is a Rabbit Polyclonal antibody against NF2 (pS518). This gene encodes a protein that is similar to some members of the ERM (ezrin, radixin, moesin) family of proteins that are thought to link cytoskeletal components with proteins in the cell membrane. This gene product has been shown to interact with cell-surface proteins, proteins involved in cytoskeletal dynamics and proteins involved in regulating ion transport. This gene is expressed at high levels during embryonic development; in adults, significant expression is found in Schwann cells, meningeal cells, lens and nerve. Mutations in this gene are associated with neurofibromatosis type II which is characterized by nervous system and skin tumors and ocular abnormalities. Two predominant isoforms and a number of minor isoforms are produced by alternatively spliced transcripts. |
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| Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S518 of human NF2. |
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| Other Names | ACN; SCH; BANF; Merlin; Moesin-ezrin-radixin-like protein; Neurofibromin-2; Schwannomerlin; Schwannomin; NF2 |
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| Gene, Accession # | NF2, Gene ID: 4771, SwissProt: P35240 |
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| Catalog # | abx000461 |
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| Price | |
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| Order / More Info | NF2 (pS518) Antibody from ABBEXA |
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| Product Specific References | n/a |
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