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| Antigenic Specificity | CD262 |
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| Clone | polyclonal |
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| Host Species | Goat |
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| Reactive Species | mouse |
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| Isotype | n/a |
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| Format | n/a |
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| Size | 0.1 mg |
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| Concentration | IgG concentration 1.0 mg/ml |
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| Applications | ELISA (EIA), Flow cytometry (FC/FACS), Immunohistology Paraffin |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | GOAT ANTI HUMAN CD262. This item recognises CD262, otherwise known as DR5/TRAIL-R2, a broadly expressed death domain containing receptor and member of the TNF-receptor superfamily, which acts as a mediator for CD253/TRAIL induced apoptosis in a variety of tumor and transformed cells, but not in normal cells. Expression of CD262 is regulated by tumor suppressor p53, and CD262 is highly expressed by tumour cell lines. Studies suggest that the death domain containing adaptor protein FADD, is requir |
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| Immunogen | Synthetic peptide APQQKRSSPSEGLCPPGHHISEDGRDC corresponding to amino acids 68-94 of the extracellular domain of human CD262.Histology Positive Control Tissue: Spleen |
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| Other Names | tumor necrosis factor receptor superfamily member 10B isoform 1; Tumor necrosis factor receptor superfamily member 10B; tumor necrosis factor receptor superfamily member 10B; Fas-like protein; TNF receptor superfamily member 10b; TNF-related apoptosis-inducing ligand receptor 2; apoptosis inducing protein TRICK2A/2B; apoptosis inducing receptor TRAIL-R2; cytotoxic TRAIL receptor-2; death domain containing receptor for TRAIL/Apo-2L; death receptor 5; p53-regulated DNA damage-inducible cell death |
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| Gene, Accession # | CD262, Gene ID: 8795, NCBI: NP_003833.4 |
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| Catalog # | MBS224046 |
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| Price | |
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| Order / More Info | CD262 Antibody from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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