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Product Name | CD46, human recombinant |
Description | Membrane cofactor protein isoform 14, also known as CD46, is a type I membrane protein that has cofactor activity for inactivation of complement components C3b and C4b by serum factor I. This function resides in the complement control protein repeats (CCPs), with CCP1-4 essential for regulation. CD46 is widely distributed on thymocytes, T cells, B cells, monocytes, granulocytes, NK cells, platelets, endothelial cells, epithelial cells, fibroblasts, placenta and sperm, but not on erythrocyte. Recombinant human CD46 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques. MW: 33.8 kDa (302 aa, 35-313 aa + His tag), confirmed by MALDI-TOF. Purity ≥85% |
Size | 100 µg |
Concentration | 1 mg/ml |
Applications | RUO |
Other Names | Membrane cofactor protein isoform 14, AHUS2, MCP, MIC10, TLX, TRA2.10 |
Gene, Accession, CAS # | CD46, Gene ID: 4179, Accession: P15529 |
Catalog # | 7314-100 |
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Order / More Info | CD46, human recombinant from BIOVISION, INC. |
Product Specific References | n/a |
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