| 产品详情 |
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| Antigenic Specificity | Conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (aa 728-745), (C-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | IKBKA(INHIBITOR OF KAPPA LIGHT POLYPEPTIDE GENE ENHANCER IN B CELLS, KINASE OF, ALPHA), also called CHUK, NFKBIKA, IKKA, IKK1, I-KAPPA-B, is a protein kinase that in humans is encoded by the CHUK gene. And it is a member of the protein kinase superfamily. And the protein contains a serine/threonine kinase domain, due to its ubiquitous expression in a broad array of tissues and high degree of conservation across species. By FISH, the IKBKA gene is mapped to chromosome 10q24. Phosphorylation of serine residues on the I-kappa-B proteins by kinases(IKBKA or IKBKB) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. IKK-alpha is part of the I kappa B kinase complex that plays an important role in regulating the NF-kappa B transcription factor. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human IKK alpha(728-745aa NEEQGNSMMNLDWSWLTE). |
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| Other Names | ikk|ikk1|ikka|ikkalpha|CHUK|IKBKA|IKK-alpha|IKK1|IKKA|NFKBIKA|TCF16|AI256658|Chuk1|Fbx24|Fbxo24|Ikka|zgc:56539 |
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| Gene, Accession # | Gene ID: 1147 |
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| Catalog # | ABIN1673091 |
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| Price | |
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| Order / More Info | Conserved Helix-Loop-Helix Ubiquitous Kinase (CHUK) (aa 728-745), (C-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 21602037, 7558004, 12789343, 10195894 |
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