产品详情 |
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Antigenic Specificity | CD44 (CD44) (N-Term) |
Clone | MEM-263 |
Host Species | Mouse |
Reactive Species | human, porcine, dog |
Isotype | IgG1 |
Format | Protein A purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)),Immunoprecipitation (IP),Flow Cytometry (FACS),Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | CD44 is a transmembrane glycoprotein expressed on the surface of most cells, which serves as a receptor for hyaluronan. CD44 mediates angiogenesis, cell adhesion, proliferation and migration, it is thus important for lymphocyte activation, recirculation and homing, it can thus serve e.g. as a modulator of macrophage recruitment in response to pathogen. Although CD44 functions are essential for physiological activities of normal cells, elevated CD44 expression correlates with poor prognosis in many carcinomas, facilitating tumour growth and metastasis, antiapoptosis and directional motility of cancer cells. |
Immunogen | COS-7 cells (African Green Monkey). |
Other Names | AU023126|AW121933|AW146109|HERMES|Ly-24|Pgp-1|CD44A|METAA|RHAMM|CDW44|CSPG8|ECMR-III|HCELL|HUTCH-I|IN|LHR|MC56|MDU2|MDU3|MIC4|Pgp1 |
Gene, Accession # | Gene ID: 960,403939,100525150 |
Catalog # | ABIN94121 |
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Order / More Info | CD44 (CD44) (N-Term) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 17599831, 18310505, 18311596, 21637782, 17446529, 18077444, 17945213, 17349212 |
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