产品名称 PTEN Antibody from BOSTER BIO
产品货号 PB9385
产品价格 现货询价,电话:010-67529703
产品规格 100ug (sample available)
产品品牌 BOSTER BIO
产品概述
产品详情
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Antigenic SpecificityPTEN
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, rat (predicted: bovine, canine, horse, monkey, rabbit)
Isotypen/a
Formatimmunogen affinity purified
Size100ug (sample available)
Concentration500ug/ml.
ApplicationsWB
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DescriptionRabbit IgG polyclonal Picoband™ antibody for Phosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN(PTEN) detection. Tested with WB in Human;Rat. No cross reactivity with other proteins. PTEN is also known as BZS, DEC, CWS1, GLM2, MHAM, TEP1, PTEN1. It is mapped to 10q23.3. This gene was identified as a tumor suppressor that is mutated in a large number of cancers at high frequency. The protein encoded by this gene is a phosphatidylinositol-3,4,5-trisphosphate 3-phosphatase. It contains a tensin like domain as well as a catalytic domain similar to that of the dual specificity protein tyrosine phosphatases. Unlike most of the protein tyrosine phosphatases, this protein preferentially dephosphorylates phosphoinositide substrates. The PTEN structure reveals a phosphatase domain that is similar to protein phosphatases but also has an enlarged active site important for the accommodation of the phosphoinositide substrate.
ImmunogenE.coli-derived human PTEN recombinant protein (Position: E91-V403). Human PTEN shares 99.7% amino acid (aa) sequence identity with mouse PTEN.
Other NamesPhosphatidylinositol 3,4,5-trisphosphate 3-phosphatase and dual-specificity protein phosphatase PTEN;3.1.3.16;3.1.3.48;3.1.3.67;Mutated in multiple advanced cancers 1;Phosphatase and tensin homolog;PTEN;MMAC1, TEP1;
Gene, Accession #PTEN, UniProt: P60484
Catalog #PB9385
Price
Order / More InfoPTEN Antibody from BOSTER BIO
Product Specific Referencesn/a
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