产品名称 Glutamate Receptor, Ionotropic, AMPA 1 (GRIA1) (aa 881-895), (C-Term) Antibody from ANTIBODIES-ONLINE GmbH
产品货号 ABIN1673061
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 ANTIBODIES-ONLINE GmbH
产品概述
产品详情
Edit&nbsp
Antigenic SpecificityGlutamate Receptor, Ionotropic, AMPA 1 (GRIA1) (aa 881-895), (C-Term)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesrat
Isotypen/a
Formatimmunogen affinity purified
Size100 µg
Concentrationn/a
ApplicationsWestern Blotting (WB)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionGLUR1, Glutamate receptor 1, is a protein that in humans is encoded by the GLUR1 gene. The sequence of GLUR1 was predicted to encode a 907-amino acid protein that had 97% identity to one of the rodent kainate receptor subunits. GLUR1 mRNA is widely expressed in human brain. Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. These receptors are heteromeric protein complexes with multiple subunits, each possessing transmembrane regions, and all arranged to form a ligand-gated ion channel. The classification of glutamate receptors is based on their activation by different pharmacologic agonists. The GRIA1 belongs to a family of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate(AMPA) receptors. Each of the members(GRIA1-4) include flip and flop isoforms generated by alternative RNA splicing. The receptor subunits encoded by each isoform vary in their signal transduction properties. The isoform presented here is the flop isoform. In situ hybridization experiments showed that human GRIA1 mRNA is present in granule and pyramidal cells in the hippocampal formation.
ImmunogenA synthetic peptide corresponding to a sequence at the C-terminus of human Glutamate Receptor 1(881-895aa HDFPKSMQSIPCMSH), different from the related rat and mouse sequences by one amino acid.
Other NamesGRIA1|glur1|GluA1|gluR-A|GLUH1|GLUR1|GLURA|HBGR1|2900051M01Rik|Glr-1|Glr1|GluR-A|GluRA|Glur-1|Glur1|HIPA1|gluR-K1
Gene, Accession #Gene ID: 50592
Catalog #ABIN1673061
Price
Order / More InfoGlutamate Receptor, Ionotropic, AMPA 1 (GRIA1) (aa 881-895), (C-Term) Antibody from ANTIBODIES-ONLINE GmbH
Product Specific ReferencesPubMed: 23271319, 12628184, 8420792
产品资料