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Antigenic Specificity | Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (aa 652-807) |
Clone | 7G6 |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 0.1 mg |
Concentration | n/a |
Applications | ELISA,Flow Cytometry (FACS),Western Blotting (WB) |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. This gene product belongs to a family of glutamate receptors that are sensitive to alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate (AMPA), and function as ligand-activated cation channels. These channels are assembled from 4 related subunits, Gria1-4. The subunit encoded by this gene (Gria2) is subject to RNA editing (Q/R and R/G), which is thought to render the channels impermeable to Ca(2+), and to affect the kinetic aspects of these channels in rat brain. Alternative splicing, resulting in transcript variants encoding different isoforms (flip and flop), has been noted for this gene. |
Immunogen | Purified recombinant fragment of human GRIA2 (AA 652-807) expressed in E. coli. |
Other Names | GLUR2|GluA2|GLURB|GluR-K2|HBGR2|GluR2|gluR-B|glur2|GluR-2|GluR-B|Glur-2|Glur2 |
Gene, Accession # | Gene ID: 2891 |
Catalog # | ABIN969524 |
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Order / More Info | Glutamate Receptor, Ionotropic, AMPA 2 (GRIA2) (aa 652-807) Antibody from ANTIBODIES-ONLINE GmbH |
Product Specific References | PubMed: 20422983, 21527319 |
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