产品名称 Glutamate Receptor, Ionotrophic, AMPA 3 (GRIA3) Antibody from ANTIBODIES-ONLINE GmbH
产品货号 ABIN1683625
产品价格 现货询价,电话:010-67529703
产品规格 50 µg
产品品牌 ANTIBODIES-ONLINE GmbH
产品概述
产品详情
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Antigenic SpecificityGlutamate Receptor, Ionotrophic, AMPA 3 (GRIA3)
Clonepolyclonal
Host SpeciesRabbit
Reactive Speciesmouse, rat, human
Isotypen/a
Formataffinity purified
Size50 µg
Concentrationn/a
ApplicationsWestern Blotting (WB),Immunohistochemistry (IHC)
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionAMPA- (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), kainite- and NMDA- (N-methyl-D-aspartate) receptors are the three main families of ionotropic glutamate-gated ion channels. AMPA receptors (AMPARs) are comprised of four subunits (GluR 1-4) that assemble as homo- or hetero-tetramers and mediate the majority of fast excitatory transmissions in the CNS. AMPARs are implicated in synapse formation, stabilization and plasticity. Post-transcriptional modifications (alternative splicing and nuclear RNA editing) and post-translational modifications (glycosylation, phoshorylation) result in a very large number of permutations, fine-tuning the kinetic properties of AMPARs . GluR 3 knockout mice exhibited normal basal synaptic transmission and long-term depression (LTD) but enhanced long-term potentiation (LTP). In contrast, GluR 2/3 double knockout mice are impaired in basal synaptic transmission . Aberrant GluR 3 expression or activity is implicated in a number of diseases, including autoimmune epilepsy, X-linked mental retardation, Retts syndrome, amyotrophic lateral sclerosis and Alzheimer disease . Synonyms: GLUR3, GLURC, GluA3, MRX94, GLUR-C, GLUR-K3
ImmunogenRecombinant protein of human GRIA3
Other NamesAMPA|gria3|GRIN3A|glur3b|gria3.2|zfGRIA3[b]|si:bz1o18.1|SI:zC231H1.1|si:zc140k5.3|GLUR3|GLUR-C|GLUR3/C|GRIA3|glur3|GluA3|GluR-3|GluR-C|GluR-K3|GLUR-K3|GLURC|MRX94|2900064I19Rik|Glur-3|Glur3|Gluralpha3
Gene, Accession #Gene ID: 2892,53623,29628
Catalog #ABIN1683625
Price
Order / More InfoGlutamate Receptor, Ionotrophic, AMPA 3 (GRIA3) Antibody from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
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