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| Antigenic Specificity | Glutamate Receptor, Ionotrophic, AMPA 3 (GRIA3) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | mouse, rat, human |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 200 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB),Immunohistochemistry (IHC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | AMPA- (alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid), kainite- and NMDA- (N-methyl-D-aspartate) receptors are the three main families of ionotropic glutamate-gated ion channels. AMPA receptors (AMPARs) are comprised of four subunits (GluR 1-4) that assemble as homo- or hetero-tetramers and mediate the majority of fast excitatory transmissions in the CNS. AMPARs are implicated in synapse formation, stabilization and plasticity. Post-transcriptional modifications (alternative splicing and nuclear RNA editing) and post-translational modifications (glycosylation, phoshorylation) result in a very large number of permutations, fine-tuning the kinetic properties of AMPARs. GluR 3 knockout mice exhibited normal basal synaptic transmission and long-term depression (LTD) but enhanced long-term potentiation (LTP). In contrast, GluR 2/3 double knockout mice are impaired in basal synaptic transmission. Aberrant GluR 3 expression or activity is implicated in a number of diseases, including autoimmune epilepsy, X-linked mental retardation, Retts syndrome, amyotrophic lateral sclerosis and Alzheimer disease.Synonyms: GLUR3, GLURC, GluA3, MRX94, GLUR-C, GLUR-K3 |
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| Immunogen | Recombinant protein of human GRIA3 |
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| Other Names | AMPA|gria3|GRIN3A|glur3b|gria3.2|zfGRIA3[b]|si:bz1o18.1|SI:zC231H1.1|si:zc140k5.3|GLUR3|GLUR-C|GLUR3/C|GRIA3|glur3|GluA3|GluR-3|GluR-C|GluR-K3|GLUR-K3|GLURC|MRX94|2900064I19Rik|Glur-3|Glur3|Gluralpha3 |
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| Gene, Accession # | Gene ID: 2892,53623,29628 |
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| Catalog # | ABIN1514130 |
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| Price | |
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| Order / More Info | Glutamate Receptor, Ionotrophic, AMPA 3 (GRIA3) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | n/a |
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