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Product Name | CYC-116 |
Description | CYC116 is a potent inhibitor of Aurora A and B with Ki value of 8 nM and 9.2 nM, respectively. It is significantly less potent against a panel of cyclin-dependent kinases and other related kinases, with the exception of Flt-3 (Ki = 44 nM). CYC-116 displays broad-spectrum antiproliferative activity against a panel of human cancer cell lines with a mean IC50 value of 0.54 µM (range = 0.09 - 1.6 µM). MW: 368.46. Purity ≥98% by HPLC |
Size | 25 mg |
Concentration | n/a |
Applications | n/a |
Other Names | 4-methyl-5-[2-(4-morpholin-4-ylanilino)pyrimidin-4-yl]-1,3-thiazol-2-amine |
Gene, Accession, CAS # | CAS: 693228-63-6 |
Catalog # | B1936-25 |
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Order / More Info | CYC-116 from BIOVISION, INC. |
Product Specific References | n/a |
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