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| Product Name | EUK 134 |
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| Description | Purity >98%. Synthetic manganese-porphyrin complexes have been documented to act as scavengers for oxidative species such as peroxynitrite, superoxide, and hydrogen peroxide. EUK 134 is a salen-manganese complex that has been modified to increase its catalase activity while retaining SOD activity. EUK 134 is a salen-manganese complex that has been modified to increase its catalase activity while retaining SOD activity. EUK 134 consumes hydrogen peroxide with an initial reaction rate of 234 µM/min in vitro . EUK 134 is protective in a rat stroke model, employing middle cerebral artery ligation. At 2.5 mg/kg, rats treated with EUK 134 showed reduced infarct volume by more than 80%. EUK 134 at 10 mg/kg also significantly attenuates brain damage in rats following systemic administration of kainic acid. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | chloro[[2,2'-[1,2-ethanediylbis[(nitrilo-?N)methylidyne]]bis [6-methoxyphenolato-?O]]]-manganese |
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| Gene, Accession, CAS # | CAS: 81065-76-1 |
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| Catalog # | LS-H7740 |
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| Order / More Info | EUK 134 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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