产品详情 |
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Antigenic Specificity | LIG4 |
Clone | CBYJL-1663 |
Host Species | Recombinant Mouse |
Reactive Species | human |
Isotype | IgG2a, κ |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | ELISA |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Mouse Anti-LIG4 Recombinant Antibody (CBYJL-1663). Provided herein is a Mouse monoclonal antibody, which binds to Dna Ligase 4 (LIG4). The antibody can be used for immunoassay techniques, such as ELISA. LIG4 is a DNA ligase that joins single-strand breaks in a double-stranded polydeoxynucleotide in an ATP-dependent reaction. LIG4 is essential for V(D)J recombination and DNA double-strand break (DSB) repair through nonhomologous end joining (NHEJ). This protein forms a complex with the X-ray repair cross complementing protein 4 (XRCC4), and further interacts with the DNA-dependent protein kinase (DNA-PK). Both XRCC4 and DNA-PK are known to be required for NHEJ. The crystal structure of the complex formed by this protein and XRCC4 has been re |
Immunogen | LIG4 (AAH37491, aa 802-911 partial recombinant protein with GST tag. MW of the GST tag alone is 26 kDa.Immunogen type: GST fusion protein. |
Other Names | LIG4S |
Gene, Accession # | Gene ID: 3981, UniProt: P49917 |
Catalog # | CBMAB-L1533-YJ |
Price | |
Order / More Info | LIG4 Antibody from CREATIVE BIOLABS |
Product Specific References | n/a |
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