产品名称 Smac/Diablo Antibody from BOSTER BIO
产品货号 PB9860
产品价格 现货询价,电话:010-67529703
产品规格 100ug (sample available)
产品品牌 BOSTER BIO
产品概述
产品详情
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Antigenic SpecificitySmac/Diablo
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat
Isotypen/a
Formatimmunogen affinity purified
Size100ug (sample available)
Concentration500ug/ml.
ApplicationsELISA, IHC, WB
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DescriptionRabbit IgG polyclonal Picoband™ antibody for Diablo homolog, mitochondrial(DIABLO) detection. Tested with WB, IHC-P, ELISA in Human;Mouse;Rat. No cross reactivity with other proteins. Diablo homolog (DIABLO), also referred to as second mitochondria-derived activator of caspases or SMAC, is a mitochondrial protein that in humans is encoded by the DIABLO (direct IAP binding protein with low pI) gene on chromosome 12. The encoded mitochondrial protein enters the cytosol when cells undergo apoptosis, and allows activation of caspases by binding to inhibitor of apoptosis proteins. Overexpression of the encoded protein sensitizes tumor cells to apoptosis. A mutation in this gene is associated with young-adult onset of nonsyndromic deafness-64. Alternative splicing results in multiple transcript variants encoding different isoforms.
ImmunogenE. coli-derived human Smac/Diablo recombinant protein (Position: A56-D239). Human Smac/Diablo shares 88.6% amino acid (aa) sequence identity with mouse Smac/Diablo.
Other NamesDiablo homolog, mitochondrial;Direct IAP-binding protein with low pI;Second mitochondria-derived activator of caspase;Smac;DIABLO;SMAC;
Gene, Accession #DIABLO, UniProt: Q9NR28
Catalog #PB9860
Price
Order / More InfoSmac/Diablo Antibody from BOSTER BIO
Product Specific Referencesn/a
产品资料