| 产品详情 |
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| Antigenic Specificity | Family with Sequence Similarity 175, Member A (FAM175A) (His6), (N-Term), (aa 1-313) |
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| Clone | ABRA1-01 |
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| Host Species | Mouse |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | Protein A purified |
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| Size | 0.1 mg |
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| Concentration | n/a |
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| Applications | Immunoprecipitation (IP),Flow Cytometry (FACS),Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ABRA1 (Abraxas), also known as CCDC98, is an adaptor protein that is essential for formation and function of BRCA1 A tumor suppressor complex. This complex plays critical roles in DNA repair, cell cycle checkpoint control, and maintenance of genomic stability. ABRA1 mediates interaction of ubiquitin-interacting motif-containing protein RAP80 and deubiquitination enzyme BRCC36 with BRCA1/BARD1. ABRA1 controls both DNA-damage-induced formation of BRCA1 foci and BRCA1-dependent G2/M checkpoint activation. |
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| Immunogen | Recombinant protein corresponding to amino acids 1-313 of ABRA1 with N-terminal His6 tag |
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| Other Names | CCDC98|abra1|ccdc98|fam175a|ABRA1|3830405G04Rik|5630400M01Rik|AI506069|AL024423|AV118690|Ccdc98|RGD1305287|zgc:103522 |
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| Gene, Accession # | Gene ID: 84142 |
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| Catalog # | ABIN1302443 |
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| Price | |
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| Order / More Info | Family with Sequence Similarity 175, Member A (FAM175A) (His6), (N-Term), (aa 1-313) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 18077395, 17643121, 17525340 |
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