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| Antigenic Specificity | COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) (aa 318-334), (C-Term) |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 µg |
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| Concentration | n/a |
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| Applications | Western Blotting (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | COP9 constitutive photomorphogenic homolog subunit 5(Arabidopsis), also known as COPS5 or JAB1, is a gene conserved from humans to Saccharomyces cerevisiae. It is a member of the MOV34 family. COPS5 is mapped to 8q13.1. The protein encoded by this gene is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling pathways. COPS5 can interact with the cytoplasmic domain of the beta-2 subunit of the alpha-L/beta-2 integrin LFA1, and it is the only protein demonstrated to interact with MIF. COPS5, VHL, and TRC8 proteins appear to be linked both physically and functionally, and all 3 may participate in the development of kidney cancer. In addition to that, COPS5 is an essential cofactor for the apoptotic function of E2F1. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the C-terminus of human JAB1(318-334aa LMSQVIKDKLFNQINIS), different from the related mouse and rat sequences by two amino acids. |
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| Other Names | BcDNA.LD14392|BcDNA:LD14392|CG14884|CH5|CSN-5|Csn5|DCH5|Dch5|Dmel\\CG14884|JAB1|JAB1/CSN5|Jab1|JadBp|csn5|dch5|jab1/csn5|l(3)89Cf|l(3)L4032|l(3)M203|quo|COPS5|MGC76063|AI303502|CSN5|Mov34|Sgn5|zgc:73130|MOV-34|SGN5 |
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| Gene, Accession # | Gene ID: 10987,26754,312916 |
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| Catalog # | ABIN1889213 |
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| Price | |
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| Order / More Info | COP9 Constitutive Photomorphogenic Homolog Subunit 5 (Arabidopsis) (COPS5) (aa 318-334), (C-Term) Antibody from ANTIBODIES-ONLINE GmbH |
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| Product Specific References | PubMed: 10766246, 16481464 |
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