| 产品详情 |
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| Antigenic Specificity | PAPPA |
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| Clone | 1-1 |
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| Host Species | Recombinant Mouse |
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| Reactive Species | human |
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| Isotype | IgG1, κ |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | WB, ELISA, IHC, IHC-P |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Mouse Anti-PAPPA Recombinant Antibody (1-1). Provided herein is a Mouse monoclonal antibody against Human Pappalysin 1. The antibody can be used for immunoassay techniques, such as WB, ELISA, IHC, IHC-P. PAPPA is a secreted metalloproteinase which cleaves insulin-like growth factor binding proteins (IGFBPs). Following IGFBP cleavage, insulin growth factors dissociate from IGFBPs and bind to IGF receptors, resulting in activation of the IGF pathway. The encoded protein plays a role in bone formation, inflammation, wound healing and female fertility. Enhanced expression of this protein is associated with diabetic nephropathy in human patients and this protein may promote tumor invasion and growth in various human cancers. |
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| Immunogen | Purified human PAPP-A adsorbed onto aluminum hydroxide gel |
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| Other Names | Pappalysin 1; Insulin-Like Growth Factor-Dependent IGF Binding Protein-4 Protease; Pregnancy-Associated Plasma Protein A, Pappalysin 1; Differentially Placenta 1 Expressed Protein; Aspecific BCL2 ARE-Binding Protein 2; IGF-Dependent IGFBP-4 Protease; IGFBP-4ase; PAPP-A; Insulin-Like Growth Factor-Dependent IGF-Binding Protein 4 Protease; |
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| Gene, Accession # | Gene ID: 5069, UniProt: Q13219 |
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| Catalog # | CBMAB-P0755-YC |
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| Price | |
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| Order / More Info | PAPPA Antibody from CREATIVE BIOLABS |
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| Product Specific References | n/a |
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| 产品资料 |
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