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| Antigenic Specificity | MDM2 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | n/a |
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| Isotype | n/a |
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| Format | n/a |
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| Size | 0.05 mg |
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| Concentration | IgG concentration 0.5mg/ml |
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| Applications | ELISA (EIA), Western Blot (WB) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | RABBIT ANTI MOUSE MDM2. This item detects murine Mdm2, a nuclear phosphoprotein that controls intracellular levels of the tumour suppressor protein p53 by ubiquitination and subsequent proteasomal degradation. Mdm2 also interacts with the retinoblastoma (RB) protein and E2F-1, to promote G1-S phase transition in the cell cycle. Mdm2 activity is controlled by self-ubiquitination; however activation of the PI3K/PKB pathway leads to phosphorylation of Mdm2 at Ser185, which stabilises the |
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| Immunogen | Synthetic peptide corresponding to aa 177-195 of mouse Mdm2. |
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| Other Names | E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase Mdm2; E3 ubiquitin-protein ligase Mdm2; double minute 2 protein; oncoprotein Mdm2; p53-binding protein Mdm2; transformed mouse 3T3 cell double minute 2; Double minute 2 protein; Oncoprotein Mdm2; p53-binding protein Mdm2, Mdm2; Mdm2; Mdm-2; AA415488; 1700007J15Rik |
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| Gene, Accession # | MDM2, Gene ID: 17246, NCBI: NP_001275515.1, UniProt: P23804 |
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| Catalog # | MBS222809 |
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| Price | |
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| Order / More Info | MDM2 Antibody from MYBIOSOURCE INC. |
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| Product Specific References | n/a |
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