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| Antigenic Specificity | CD161 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | Protein A purified |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | WB, IHC-P, IF(IHC-P) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | CD161 Polyclonal Antibody. • Target Background: Plays an inhibitory role on natural killer (NK) cells cytotoxicity. Activation results in specific acid sphingomyelinase/SMPD1 stimulation with subsequent marked elevation of intracellular ceramide. Activation also leads to AKT1/PKB and RPS6KA1/RSK1 kinases stimulation as well as markedly enhanced T-cell proliferation induced by anti-CD3. Acts as a lectin that binds to the terminal carbohydrate Gal-alpha(1,3)Gal epitope as well as to the N-acetyllactosamine epitope. Binds also to CLEC2D/LLT1 as |
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| Immunogen | KLH conjugated synthetic peptide derived from human CD161/NK11. Immunogen Range: 175-225/225 |
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| Other Names | NKR; CD161; CLEC5B; NKR-P1; NKRP1A; NKR-P1A; hNKR-P1A; Killer cell lectin-like receptor subfamily B member 1; C-type lectin domain family 5 member B; Natural killer cell surface protein P1A; KLRB1 |
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| Gene, Accession # | Gene ID: 3820, SwissProt: Q12918 |
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| Catalog # | bs-2807R |
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| Price | |
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| Order / More Info | CD161 Antibody from BIOSS ANTIBODIES |
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| Product Specific References | n/a |
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