| 产品详情 |
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| Antigenic Specificity | ATM |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, mouse, rat |
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| Isotype | n/a |
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| Format | Protein A purified |
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| Size | 100ul |
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| Concentration | 1ug/ul |
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| Applications | FCM, IHC-P, IF(IHC-P), IF(ICC) |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | ATM Polyclonal Antibody. • Target Background: Serine/threonine protein kinase which activates checkpoint signaling upon double strand breaks (DSBs), apoptosis and genotoxic stresses such as ionizing ultraviolet A light (UVA), thereby acting as a DNA damage sensor. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX at double strand breaks (DSBs), thereby regulating DNA damage response mechanism. Also plays a role in pre-B cell allelic exclusion, a process leading to expression of a sing |
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| Immunogen | KLH conjugated synthetic peptide derived from mouse ATM. Immunogen Range: 2700-2750/3066 |
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| Other Names | AI256621; C030026E19Rik; Serine-protein kinase ATM; Ataxia telangiectasia mutated homolog; A-T mutated homolog; Atm |
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| Gene, Accession # | Gene ID: 11920, SwissProt: Q62388 |
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| Catalog # | bs-1370R |
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| Price | |
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| Order / More Info | ATM Antibody from BIOSS ANTIBODIES |
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| Product Specific References | Liu, Jianhui, et al. (2017) Environ Sci Pollut Res Int. PubMed: 29151191 |
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