产品详情 |
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Antigenic Specificity | APBB1 |
Clone | BA0242 |
Host Species | Recombinant Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | purified |
Size | n/a |
Concentration | n/a |
Applications | WB, IHC-P, ICC |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit Anti-APBB1 Recombinant Antibody (BA0242). This product is a rabbit antibody that recognizes APBB1. The antibody BA0242 can be used for immunoassay techniques such as: WB, IHC-P, ICC. Hu et al. (1998) detected several polymorphisms in the FE65 gene. In the 84-bp intron (intron 13), which interrupts 2 exons encoding the APP binding site, they found a biallelic polymorphism. The frequency of the minor allele in this intron was 0.097 in dementia of the Alzheimer type (DAT) cases and 0.161 in controls. APP functions as a cytosolic anchoring site that can prevent the gene product's nuclear translocation. May act by specifically recognizing and binding histone H2AX phosphorylated on 'Tyr-142' (H2AXY142ph) at double-strand breaks (DSBs), rec |
Immunogen | Synthetic peptide from residues in human FE65 |
Other Names | Amyloid Beta (A4) Precursor Protein-Binding, Family B, Member 1 (Fe65); FE65; RIR; Adaptor Protein FE65a2; Stat-Like Protein; Protein Fe65; MGC:9072 |
Gene, Accession # | Gene ID: 322, UniProt: O00213 |
Catalog # | CBMAB-0062CQ |
Price | |
Order / More Info | APBB1 Antibody from CREATIVE BIOLABS |
Product Specific References | n/a |
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