| 产品详情 |
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| Antigenic Specificity | INCENP |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human, rat |
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| Isotype | n/a |
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| Format | affinity purified |
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| Size | 100 ul, 50 ul, 200 ul |
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| Concentration | n/a |
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| Applications | WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit polyclonal antibody to INCENP. In mammalian cells, 2 broad groups of centromere-interacting proteins have been described: constitutively binding centromere proteins and passenger, or transiently interacting, proteins (reviewed by Choo, 1997). The constitutive proteins include CENPA (centromere protein A; MIM 117139), CENPB (MIM 117140), CENPC1 (MIM 117141), and CENPD (MIM 117142). The term passenger proteins encompasses a broad collection of proteins that localize to the centromere during specific stages of the cell cycle (Earnshaw and Mackay, 1994 [PubMed 8088460]). These include CENPE (MIM 117143); MCAK (MIM 604538); KID (MIM 603213); cytoplasmic dynein (e.g., MIM 600112); CliPs (e.g., MIM 179838); and CENPF/mitosin (MIM 600236). The inner centromere proteins (INCENPs) (Earnshaw and Cooke, 1991 [PubMed 1860899]), the initial members of the passenger protein group, display a broad localization along chromosomes in the early stages of mitosis but gradually become concentrated at centromeres as the cell cycle progresses into mid-metaphase. During telophase, the proteins are located within the midbody in the intercellular bridge, where they are discarded after cytokinesis |
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| Immunogen | Recombinant protein of human INCENP |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 3619, UniProt: Q9NQS7 |
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| Catalog # | orb153970 |
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| Price | |
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| Order / More Info | INCENP Antibody from BIORBYT LTD. |
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| Product Specific References | n/a |
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