产品详情 |
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Antigenic Specificity | ABCG8 |
Clone | polyclonal |
Host Species | Rabbit |
Reactive Species | human, mouse, rat |
Isotype | n/a |
Format | affinity purified |
Size | 50 µl, 100 µl, 200 µl |
Concentration | > 1 mg/ml |
Applications | WB. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | ABCG8 Antibody is a Rabbit Polyclonal antibody against ABCG8. The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. The protein encoded by this gene functions to exclude non-cholesterol sterol entry at the intestinal level, promote excretion of cholesterol and sterols into bile, and to facilitate transport of sterols back into the intestinal lumen. It is expressed in a tissue-specific manner in the liver, intestine, and gallbladder. This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG5. Mutations in this gene may contribute to sterol accumulation and atherosclerosis, and have been observed in patients with sitosterolemia. [provided by RefSeq, Jul 2008]. |
Immunogen | Recombinant protein of human ABCG8. |
Other Names | ABC-G8; STSL; Gallbladder Disease 4; Sterolin 2; ATP-binding cassette sub-family G member 8; ABCG8; GBD4 |
Gene, Accession # | ABCG8, Gene ID: 64241, SwissProt: Q9H221 |
Catalog # | abx001545 |
Price | |
Order / More Info | ABCG8 Antibody from ABBEXA |
Product Specific References | n/a |
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