产品详情 |
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Antigenic Specificity | ABCG5 |
Clone | monoclonal |
Host Species | Mouse |
Reactive Species | human |
Isotype | IgG1 |
Format | purified |
Size | 100 µg |
Concentration | 1.0 mg/ml |
Applications | ELISA, WB, IHC, FCM. RUO |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.ABC proteins transport various molecules across extra- and intra-cellular membranes.ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).This protein is a member of the White subfamily.The protein encoded by this gene functions as a half-transporter to limit intestinal absorption and promote biliary excretion of sterols.It is expressed in a tissue-specific manner in the liver, colon, and intestine.This gene is tandemly arrayed on chromosome 2, in a head-to-head orientation with family member ABCG8.Mutations in this gene may contribute to sterol accumulation and atheroschlerosis, and have been observed in patients with sitosterolemia. |
Immunogen | Purified recombinant fragment of human ABCG5 (AA: 306-367) expressed in E. coli. |
Other Names | ABC-G5; STSL; Sterolin 1; ATP-binding cassette sub-family G member 5; Sterolin; Sterolin-1 |
Gene, Accession # | ABCG5, Gene ID: 64240, SwissProt: Q9H222 |
Catalog # | abx015759 |
Price | |
Order / More Info | ABCG5 Antibody from ABBEXA |
Product Specific References | n/a |
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