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| Antigenic Specificity | catenin, beta- |
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| Clone | PY654-B-catenin (IgG) |
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| Host Species | Mouse |
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| Reactive Species | African green monkey, chicken, mouse, rat |
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| Isotype | IgG1 |
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| Format | HYBRIDOMA |
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| Size | 1 vial cells |
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| Concentration | n/a |
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| Applications | Immunofluorescence, Immunoprecipitation, Western Blot |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Epitope: NH2-CELLHSRNEGVATPYAA-OH. Fusion: 09/05. This antibody is specific to beta-catenin phosphorylated at Tyr 654. Beta-1 Catenin is a Key downstream component of the canonical Wnt signaling pathway whose function is affected by differential phosphorylation. Specificity tested on Y654F beta-catenin. See mAb PY489-B-catenin for an antibody specific to beta-catenin phosphorylated at Tyr 489. The catenin target of PY489-B-catenin has been described as nuclear-bound, and the target of PY654-B-catenin (IgG) has been described as membrane-bound/cytoplasmic [PMID 25367124]. |
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| Immunogen | syntetic phospho-peptide: NH2-CELLHSRNEGVATPYAA-OH |
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| Other Names | Bfc; Mesc; Catnb |
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| Gene, Accession # | Ctnnb1, Gene ID: 12387, UniProt: Q02248 |
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| Catalog # | PY654-B-catenin (IgG) |
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| Price | |
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| Order / More Info | catenin, beta- Antibody from DEVELOPMENTAL STUDIES HYBRIDOMA BANK |
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| Product Specific References | PubMed: 17618275, 25367124, 26663639, 21520058, 22203675 |
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