| 产品详情 |
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| Antigenic Specificity | catenin, beta- |
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| Clone | PY489-B-catenin |
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| Host Species | Mouse |
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| Reactive Species | chicken, mouse |
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| Isotype | IgM |
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| Format | HYBRIDOMA |
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| Size | 1 vial cells |
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| Concentration | n/a |
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| Applications | Immunofluorescence, Immunohistochemistry, Western Blot |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Epitope: NH2-CRHQEAEMAQNAVRLHPYGL-OH. Fusion: 09/05. This antibody is specific to beta-catenin phosphorylated at Tyr 489. Beta-1 Catenin is a Key downstream component of the canonical Wnt signaling pathway whose function is affected by differential phosphorylation. Specificity tested on Y489F beta-catenin. See mAb PY654-B-catenin (IgG) for an antibody specific to beta-catenin phosphorylated at Tyr 654. The catenin target of PY489-B-catenin has been described as nuclear-bound/active beta-catenin, and the target of PY654-B-catenin (IgG) has been described as membrane-bound/cytoplasmic beta-catenin. |
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| Immunogen | syntetic phospho-peptide: NH2-CRHQEAEMAQNAVRLHPYGL-OH |
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| Other Names | Bfc; Mesc; Catnb |
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| Gene, Accession # | Ctnnb1, Gene ID: 12387, UniProt: Q02248 |
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| Catalog # | PY489-B-catenin |
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| Price | |
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| Order / More Info | catenin, beta- Antibody from DEVELOPMENTAL STUDIES HYBRIDOMA BANK |
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| Product Specific References | PubMed: 17618275, 22383889, 17618275, 25367124, 23097346, 19700620, 22461561, 21239885, 23074223, 17618275, 23074223 |
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