| 产品详情 |
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| Antigenic Specificity | CCR3 |
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| Clone | polyclonal |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | n/a |
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| Format | immunogen affinity purified |
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| Size | 100 ug |
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| Concentration | n/a |
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| Applications | ICC, IF, IHC-P, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit polyclonal to CCR3. C-C chemokine receptor type 3, also called CCR3 or CKR3 is a protein that in humans is encoded by the CCR3 gene. The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. Alternatively spliced transcript variants have been described. |
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| Immunogen | A synthetic peptide corresponding to a sequence at the N-terminus of human CCR3. |
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| Other Names | CD193, CKR3, CMKBR3, CCR-3, C-C CKR-3, CC-CKR-3, EOTAXIN RECEPTOR, Eosinophil eotaxin receptor, CHEMOKINE, CC MOTIF, RECEPTOR 3 |
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| Gene, Accession # | UniProt: P51677 |
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| Catalog # | orb137947 |
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| Price | |
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| Order / More Info | CCR3 Antibody from BIORBYT LTD. |
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| Product Specific References | n/a |
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