产品名称 RAB7/RAB7A Antibody from BOSTER BIO
产品货号 PB9883
产品价格 现货询价,电话:010-67529703
产品规格 100ug (sample available)
产品品牌 BOSTER BIO
产品概述
产品详情
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Antigenic SpecificityRAB7/RAB7A
Clonepolyclonal
Host SpeciesRabbit
Reactive Specieshuman, mouse, rat (predicted: chicken)
Isotypen/a
Formatimmunogen affinity purified
Size100ug (sample available)
Concentration500ug/ml.
ApplicationsWB
Reviews / RatingsIf you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY.
DescriptionRabbit IgG polyclonal Picoband™ antibody for Ras-related protein Rab-7a(RAB7A) detection. Tested with WB in Human;Mouse;Rat. No cross reactivity with other proteins. Ras-related protein Rab-7a is a protein that in humans is encoded by the RAB7A gene. RAB7A functions as a key regulator in endo-lysosomal trafficking, governs early-to-late endosomal maturation, microtubule minus-end as well as plus-end directed endosomal migration and positions, and endosome-lysosome transport through different protein-protein interaction cascades. Furthermore, RAB7A is involved in regulation of some specialized endosomal membrane trafficking, such as maturation of melanosomes through modulation of SOX10 and the oncogene MYC. Mutations in the lysosomal pathway result in tumor progression in melanoma cells.
ImmunogenA synthetic peptide corresponding to a sequence at the C-terminus of human RAB7 (157-196aa KEAINVEQAFQTIARNALKQETEVELYNEFPEPIKLDKND), identical to the related mouse sequence, and different from the related rat sequence by one amino acid.
Other NamesRas-related protein Rab-7a;RAB7A;RAB7;
Gene, Accession #RAB7A, UniProt: P51149
Catalog #PB9883
Price
Order / More InfoRAB7/RAB7A Antibody from BOSTER BIO
Product Specific Referencesn/a
产品资料