| 产品详情 |
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| Antigenic Specificity | Human CCR3 |
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| Clone | 34I28M2 |
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| Host Species | Rabbit |
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| Reactive Species | human |
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| Isotype | IgG |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | ICC, IF |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit Anti-Human CCR3 monoclonal antibody for ICC, IF. Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR3 (eotaxin receptor), is expressed on eosinophils and certain T cell population respond to a variety of CC chemokines apart from eotaxin, including RANTES, monocyte chemotactic protein (MCP)-2, MCP-3, and MCP-4. CCR3 facilitated infection by a more restricted subset of primary viruses, and binding of the CCR3 ligand, eotaxin, and inhibited infection by these isolates. |
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| Immunogen | Peptides corresponding to human CCR3 [1) aa 337-355; 2) aa 172-190] |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 1232, UniProt: P51677 |
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| Catalog # | CABT-L1225 |
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| Price | |
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| Order / More Info | Human CCR3 Antibody from CREATIVE DIAGNOSTICS |
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| Product Specific References | n/a |
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