产品详情 |
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Antigenic Specificity | Human CaMKII (phospho Thr305,Thr306) |
Clone | 0I3M8 |
Host Species | Rabbit |
Reactive Species | human |
Isotype | IgG |
Format | unconjugated |
Size | n/a |
Concentration | n/a |
Applications | FC, ICC, IF, WB |
Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
Description | Rabbit Anti-Human CaMKII (phospho Thr305,Thr306) monoclonal antibody for FC, ICC, IF, WB. The Ca2+/calmodulin-dependent protein kinases (CaM kinases) comprise a structurally related subfamily of serine/threonine kinases which include CaMKI, CaMKII and CaMKIV. CaMKII is an ubiquitously expressed serine/threonine protein kinase that is activated by Ca2+/calmodulin (CaM) binding and autophosphorylation and has been implicated in regulation of the cell cycle and transcription. It is involved in dendritic spine and synapse formation, neuronal plasticity and regulation of sarcoplasmic reticulum Ca2+ transport in skeletal muscle. In neurons, plays an essential structural role in the reorganization of the actin cytoskeleton during plasticity by binding and bundling actin filaments in a kinase-independent manner. |
Immunogen | Peptide corresponding to Human CMK2A (aa 300-309) |
Other Names | n/a |
Gene, Accession # | Gene ID: 818, UniProt: Q13555 |
Catalog # | CABT-L1215 |
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Order / More Info | Human CaMKII (phospho Thr305,Thr306) Antibody from CREATIVE DIAGNOSTICS |
Product Specific References | n/a |
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