| 产品详情 |
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| Antigenic Specificity | Smad4 |
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| Clone | SN388 |
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| Host Species | Rabbit |
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| Reactive Species | human, (mouse) |
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| Isotype | IgG |
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| Format | unconjugated |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | IHC, WB |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | Rabbit Anti-Human Smad4 monoclonal antibody for IHC,WB. This gene encodes a member of the Smad family of signal transduction proteins. Smad proteins are phosphorylated and activated by transmembrane serine-threonine receptor kinases in response to TGF-beta signaling. The product of this gene forms homomeric complexes and heteromeric complexes with other activated Smad proteins, which then accumulate in the nucleus and regulate the transcription of target genes. This protein binds to DNA and recognizes an 8-bp palindromic sequence (GTCTAGAC) called the Smad-binding element (SBE). The Smad proteins are subject to complex regulation by post-translational modifications. Mutations or deletions in this gene have been shown to result in pancreatic cancer, juvenile polyposis syndrome, and hereditary hemorrhagic telangiectasia syndrome. [provided by RefSeq, Oct 2009] |
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| Immunogen | A peptide corresponding to the C-terminus of human Smad4. |
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| Other Names | n/a |
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| Gene, Accession # | Gene ID: 4089, UniProt: A0A024R274 |
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| Catalog # | CABT-BL8494 |
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| Price | |
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| Order / More Info | Smad4 Antibody from CREATIVE DIAGNOSTICS |
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| Product Specific References | n/a |
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| 产品资料 |
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