| 产品详情 |
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| Product Name | Kartogenin |
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| Description | Purity >98% by HPLC. Potent, selective and non-cytotoxic downstream RUNX modulator. Potently induces the differentiation of human mesenchymal stem cells (hMSCs) into chondrocytes (EC50 = 100 nM). It shows chondroprotective effects in vitro and is efficacious in two Osteoarthritis (OA) animal models. It binds filamin A, disrupts its interaction with the transcription factor core-binding factor Beta subunit (CBFBeta) and induces chondrogenesis by regulating the CBFBeta-RUNX1 transcriptional program. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 2-[([1,1'-Biphenyl]-4-ylamino)carbonyl]benzoic acid |
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| Gene, Accession, CAS # | CAS: 4727-31-5 |
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| Catalog # | LS-H11141 |
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| Order / More Info | Kartogenin from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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