| 产品详情 |
| Edit |   |
|---|
| Antigenic Specificity | Human ALOX5 |
|---|
| Clone | H.600.3 |
|---|
| Host Species | Rabbit |
|---|
| Reactive Species | human, mouse, nonhuman primate, rat |
|---|
| Isotype | IgG |
|---|
| Format | unconjugated |
|---|
| Size | n/a |
|---|
| Concentration | n/a |
|---|
| Applications | IHC-P, IP, WB |
|---|
| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
|---|
| Description | Rabbit Anti-Human ALOX5 monoclonal antibody for IHC-P, IP, WB. This gene encodes a member of the lipoxygenase gene family and plays a dual role in the synthesis of leukotrienes from arachidonic acid. The encoded protein, which is expressed specifically in bone marrow-derived cells, catalyzes the conversion of arachidonic acid to 5(S)-hydroperoxy-6-trans-8,11,14-cis-eicosatetraenoic acid, and further to the allylic epoxide 5(S)-trans-7,9-trans-11,14-cis-eicosatetrenoic acid (leukotriene A4). Leukotrienes are important mediators of a number of inflammatory and allergic conditions. Mutations in the promoter region of this gene lead to a diminished response to antileukotriene drugs used in the treatment of asthma and may also be associated with atherosclerosis and several cancers. Alternatively spliced transcript variants have been observed, but their full-length nature has not been determined. |
|---|
| Immunogen | Synthetic peptide |
|---|
| Other Names | n/a |
|---|
| Gene, Accession # | Gene ID: 240, UniProt: P09917 |
|---|
| Catalog # | DCABH-5273 |
|---|
| Price | |
|---|
| Order / More Info | Human ALOX5 Antibody from CREATIVE DIAGNOSTICS |
|---|
| Product Specific References | n/a |
|---|
| 产品资料 |
|
|