产品名称 Galanin Receptor 2 (GALR2) peptide from ANTIBODIES-ONLINE GmbH
产品货号 ABIN936382
产品价格 现货询价,电话:010-67529703
产品规格 100 µg
产品品牌 ANTIBODIES-ONLINE GmbH
产品概述
产品详情
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Product NameGalanin Receptor 2 (GALR2) peptide
DescriptionGalanin is an important neuromodulator present in the brain, gastrointestinal system, and hypothalamopituitary axis. It is a 30-amino acid non-C-terminally amidated peptide that potently stimulates growth hormone secretion, inhibits cardiac vagal slowing of heart rate, abolishes sinus arrhythmia, and inhibits postprandial gastrointestinal motility. The actions of galanin are mediated through interaction with specific membrane receptors that are members of the 7-transmembrane family of G protein-coupled receptors. GALR2 interacts with the N-terminal residues of the galanin peptide. The primary signaling mechanism for GALR2 is through the phospholipase C/protein kinase C pathway (via Gq), in contrast to GALR1, which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi. However, it has been demonstrated that GALR2 couples efficiently to both the Gq and Gi proteins to simultaneously activate 2 independent signal transduction pathways.
Size100 µg
Concentrationn/a
ApplicationsWestern Blotting (WB),Immunohistochemistry (IHC),Blocking Peptide (BP)
Other NamesGALR2|GALNR2|mGalR
Gene, Accession, CAS #n/a
Catalog #ABIN936382
Price
Order / More InfoGalanin Receptor 2 (GALR2) peptide from ANTIBODIES-ONLINE GmbH
Product Specific Referencesn/a
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