| 产品详情 |
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| Product Name | IDO1, human recombinant |
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| Description | IDO1 is an indoleamine 2,3-dioxygenase - a heme enzyme that catalyzes the first and rate-limiting step in tryptophan catabolism to N-formyl-kynurenine. This enzyme acts on multiple tryptophan substrates including D-tryptophan, and serotonin. It is thought to play a role in a variety of pathophysiological processes such as antimicrobial and antitumor defense, neuropathology, immunoregulation, and antioxidant activity. Through its expression in dendritic cells, monocytes, and macrophages this enzyme modulates T-cell behavior by its pericellular catabolization of the essential amino acid tryptophan. Recombinant human IDO1 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniqu |
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| Size | 10 µg |
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| Concentration | 0.5 mg/ml |
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| Applications | RUO |
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| Other Names | Indoleamine 2,3-dioxygenase 1, IDO, IDO-1, INDO |
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| Gene, Accession, CAS # | IDO1, Gene ID: 3620, Accession: P14902 |
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| Catalog # | P1096-10 |
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| Order / More Info | IDO1, human recombinant from BIOVISION, INC. |
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| Product Specific References | n/a |
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