| 产品详情 |
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| Antigenic Specificity | CDH1 |
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| Clone | monoclonal |
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| Host Species | Mouse |
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| Reactive Species | human, mouse, monkey |
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| Isotype | IgG1 |
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| Format | ascites |
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| Size | 100 µl |
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| Concentration | n/a |
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| Applications | ELISA, WB, IHC, FCM. RUO |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites. [provided by RefSeq]. |
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| Immunogen | Purified recombinant fragment of human CDH1 expressed in E. Coli. |
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| Other Names | CADH1; cadherin 1; type 1; E-cadherin (epithelial) (ECAD); cadherin-1; CAM 120/80; E-cadherin; epithelial-cadherin; uvomorulin; CDH1; Arc-1; CD324; CDHE; ECAD; LCAM; UVO; E-Cad/CTF3; Epithelial cadherin; E-Cad/CTF1; E-Cad/CTF2; Um; E-cad; L-CAM; AA960649; E-Cadherin, |
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| Gene, Accession # | Gene ID: 999, SwissProt: P12830 |
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| Catalog # | abx012163 |
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| Price | |
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| Order / More Info | CDH1 Antibody from ABBEXA |
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| Product Specific References | n/a |
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