| 产品详情 |
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| Product Name | Beta-Nicotinamide Mononucleotide |
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| Description | Purity >95%. Beta-Nicotinamide mononucleotide (Beta-NMN) is an intermediate in the biosynthesis of nicotinamide adenine dinucleotide (NAD+ ). Nicotinamide phosphoribosyltransferase (Nampt) catalyzes the condensation of nicotinamide with 5-phosphoribosyl-1-pyrophosphate to generate Beta-NMN, which is subsequently converted to NAD+ by Beta-NMN adenyltransferase. At 50-100 µM, Beta-NMN has been used to enhance NAD biosynthesis and glucose-stimulated insulin secretion in a Nampt+/- mouse model of metabolic disease, demonstrating a role for Nampt in Beta cell function. Furthermore, at 500 mg/kg/day, it has been shown to ameliorate glucose intolerance in high-fat diet-induced type 2 diabetes mice by restoring NAD+ levels. |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | 3-(aminocarbonyl)-1-(5-O-phosphono-Beta-D-ribofuranosyl)-pyridinium, inner salt, -Beta-NMN |
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| Gene, Accession, CAS # | CAS: 1094-61-7 |
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| Catalog # | LS-H10624 |
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| Price | |
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| Order / More Info | Beta-Nicotinamide Mononucleotide from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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