| 产品详情 |
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| Antigenic Specificity | MyoD |
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| Clone | 5.8A |
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| Host Species | Mouse |
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| Reactive Species | human, mouse |
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| Isotype | IgG1 kappa |
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| Format | Protein G purified |
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| Size | 0.1 mg |
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| Concentration | 1.0 mg/ml |
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| Applications | Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Frozen. There is considerable literature published using the MyoD, Clone 5.8 antibody. The original development publication of the MyoD antibody, Clone 5.8A showed that the antibody detected MyoD in rhabdomysosarcomas by IHC (frozen) but not in normal adult tissues (Dias, 1992) or normal fetal skeletal muscle. The 5.8A clone also detected MyoD1 in a subset of Wilms' tumors and one ectomesenchyoma, neoplasms known to contain myogenic elements. These results led to the concept in 1992 that the 5.8A clone may be useful for differentiating rhabdomyosarcomas from other soft tissue malignancies. However, as there has been a myriad of publications since Clone 5.8A was first described, users are encourage to consult the scientific literature citing Clone 5.8A to determine the suitability of the antibody for their model system. |
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| Reviews / Ratings | If you have used this antibody, please help fellow researchers by submitting reviews to pAbmAbs and antYbuddY. |
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| Description | The MyoD Antibody (5.8A) from Novus Biologicals is a mouse monoclonal antibody to MyoD. This antibody reacts with human, mouse. The MyoD Antibody (5.8A) has been validated for the following applications: Western Blot, Immunohistochemistry, Immunocytochemistry/Immunofluorescence, Immunoprecipitation, Immunohistochemistry-Frozen. |
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| Immunogen | The 5.8A antibody was made against recombinant mouse MyoD protein but it also recognizes human (myf3), rat, and cat homologs. The epitope of this antibody was mapped to a region within aa 180-189 of mouse MyoD (NP_002469). |
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| Other Names | bHLHc1BHLHC1, Class C basic helix-loop-helix protein 1, MYF3Myf-3, MYODmyoblast determination protein 1, myogenic differentiation 1, Myogenic factor 3myf-3, PUM |
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| Gene, Accession # | MYOD1, Gene ID: 4654, Accession: P15172, P10085, SwissProt: P15172 |
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| Catalog # | NB100-56511 |
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| Price | |
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| Order / More Info | MyoD Antibody from NOVUS BIOLOGICALS, LLC |
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| Product Specific References | PubMed: 1384962, 18364460, 20566686, 21248078, 22006022, 24814716, 28286175, 29380555, 30004470, 30122554 |
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