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| Product Name | AGI-5198 |
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| Description | Purity >98% by HPLC. A potent, selective inhibitor of mutant IDH1 (isocitrate dehydrogenase 1). AGI-5198 inhibits IDH1 R132H and R132C mutants in vitro with IC50 values of 0.07 and 0.16 µM, respectively, but not wild-type IDH1, wild-type IDH2, or IDH2 mutants (IC50 s > 100 MM). Under conditions of near complete 2-HG (2-hydroxyglutarate) inhibition, AGI-5198 can induce demethylation of histone H3K9me3 and expression |
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| Size | n/a |
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| Concentration | n/a |
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| Applications | n/a |
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| Other Names | N-[2-(cyclohexylamino)-1-(2-methylphenyl)-2-oxoethyl]-N-(3-fluorophenyl)-2-methyl-1H-imidazole-1-acetamide, IDH-C35 |
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| Gene, Accession, CAS # | CAS: 1355326-35-0 |
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| Catalog # | LS-H2945 |
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| Order / More Info | AGI-5198 from LIFESPAN BIOSCIENCES INC. |
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| Product Specific References | n/a |
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